Niraparib

BNF:
Not listed
Status:
Do Not Prescribe (DNP), Red
Decision Date:
August 2018
 

Comments

RED1,2,3,8: NICE TA528 -  maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube and peritoneal cancer.

RED1,2,3,8: NICE TA784- maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube and peritoneal cancer. (Decision date - May 2022) NHSE commissioned

RED NICE TA1129: Niraparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy (Decision date March 2026)

DNP: NICE TA1032: (Terminated Appraisal) Niraparib with abiraterone acetate and prednisone for untreated hormone-relapsed metastatic prostate cancer (decision date Feb 2025)

 


Do Not Prescribe (DNP) Drug Classifications

  • 6: Have NICE guidance that recommends they should not be used

Red Drug Classifications

  • 1: Requiring specialist assessment to enable patient selection, initiation and ongoing treating
  • 2: Requiring long term on-going monitoring of efficacy by a specialist and not suitable for shared care
  • 3: Requiring long term on-going monitoring of toxicity by a specialist (either because of difficulty in recognising side effects or high cost of investigations to identify toxicity)
  • 8. NHS England commissioned – to be used in line with NHSE commissioning intentions

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